Monday 25 September 2017

The Number Of Oxygen Absorbers Are Required A Number Of Factors

Oxygen safeguards are reformed to build the time span of usability of dried out sustenance; the presence of oxygen diminishes the capacity life of nourishment and causes oxidative weakening. The little bundles of o-busters are made of material that is containing an iron powder and salt, which is not permitted to enter oxygen and dampness. Oxygen safeguards play out their activity however a compound response process.



At the point when all the iron powder has oxidized, the oxygen safeguards are stops the retaining activity.

Every bundle of oxygen safeguards contains a light pink container. This case swings to a light blue shading when bundle is opened.

The oxygen underpins the development of microbes, parasites, smells and causes changes in shade of bundled sustenances. Along these lines, the sustenance safe pockets are put on the nourishments; they won't hurt the nourishment with decreasing the vigorous condition to 0% oxygen and high-impact microscopic organisms can't develop in this condition. Oxygen safeguards are evacuate oxygen more successfully than vacuum bundling.


The Number Of Oxygen Absorbers Are Required A Number Of Factors: 

• The "cc" size of oxygen safeguard bundle you are utilizing

• The volume of the bundling compartment

• The height and measurement of the bundling

• Require the bundling compartment – box or packs

• The thickness of sustenance thing you are bundling. By doing this match, you can see that one 500cc safeguards are effectively carry out the activity

• Quantity of bundling materials

• Void space of holder.

For more data please visit our site: http://www.oxygen-absorbers.com/ 

Address: 

304-307, III Floor, Prayosha Complex,
Alongside Hyundai Motor Showroom,
Chhani Jakat Naka,
Vadodara – 390024,
Gujarat, India.

Telephone number:-
+91-756-768-8877

Sunday 17 September 2017

Role of packaging material on Pharmaceutical product packaging.!

General Overview

1. What is pharma packaging?
2. Importance of packaging
3. Functions of packaging
4. Material characteristics Choosing the Appropriate Primary Pack Suitable polymer/ Blister Packs Containers & Closures 


What is packaging ?

Packaging is defined as the collection of different components which surround the pharmaceutical product from the time of production until its use.

Importance of packaging

Protect against all adverse external influences that can alter the properties of the product.



• Protect against biological contamination.
• Protect against physical damage.
 • Carry the correct information and identification of the product.
• Tamper evident / Child resistance / Anti counterfeiting.

Functions of packaging
  • ·         Containment
  • ·         Not to leak, nor allow diffusion and permeation
  • ·         Strong enough to hold the contents during handling
  • ·         Protection
  • ·         Light
  • ·         Moisture
  • ·         Oxygen
  • ·         Biological contamination
  • ·         Mechanical damage
  • ·         Counterfeiting

Material characteristics



Additional qualities required

·         It must preserve the physical properties of all dosage 
·         Forms and protect them against damage or breakage. 
·         It must not alter the identity of the product. 
·         It must preserve the characteristics properties of the  product to comply specifications. 
·         It must protect product against undesirable or adulterating chemical, biological or physical entities. Don't miss this article:how to use triple laminated bags for pharma packaging.

Selection of packaging material
  • ·         Moisture barrier requirements 
  • ·         Light barrier requirements 
  • ·         Gas barrier requirements 
  • ·         Chemical properties

Choosing appropriate primary pack

Desiccants have been utilized to control the exposure of products to the ingress of moisture. Desiccants vary in their capacity and the rate that they adsorb/absorb ingressed moisture. Silica gel & oxygen absorber  is very efficient at absorbing moisture at high relative humidity, but comparatively poor at lower Relative Humidity. Molecular sieve desiccants - the opposite scenario prevails. As a consequence, more molecular sieve is required at higher relative humidity, and the greater the handling precautions that are required during packaging operations. Based on the calculated WVTR of known container components and the rate of moisture adsorbed by desiccants, the amount of desiccant that would be required to maintain a specified relative humidity over the product’s shelf-life can be determined and used. Also Read: Best Guidelines for Pharma packaging using LDPE bags


TESTING AND STABILITY
  1. ·         QC test - routine tests 
  2. ·         Vary according to the type of material used 
  3. ·         Visual inspection 
  4. ·         Identification test 
  5. ·         Dimensional test 
  6. ·         Physical tests 
  7. ·         Chemical tests 
  8. ·         Microbiological tests



Monday 4 September 2017

Role of packaging material on Pharmaceutical products.!

General Overview

1.       What is packaging?
2.       Importance of packaging
3.       Functions of packaging
4.       Material characteristics



Choosing the Appropriate Primary Pack

    1. Suitable polymer/ Blister Packs
    2. Containers & Closures

 What is packaging?

Packaging is defined as the collection of different components which surround the pharmaceutical
Product from the time of production until its use. Don't Miss this article : Best guidelines for pharma packaging using LDPE bags



Importance of packaging

Protect against all adverse external influences that can alter the properties of the product.

• Protect against biological contamination.
 • Protect against physical damage.
• Carry the correct information and identification of the product.
 • Tamper evident / Child resistance / Anti counterfeiting.

Function of Packaging

Containment
Not to leak, nor allow diffusion and permeation Strong enough to hold the contents during handling

Protection
·         Light
·         Moisture
·         Oxygen
·         Biological contamination
·         Mechanical damage
·         Counterfeiting

Material characteristics

Additional qualities required

·         It must preserve the physical properties of all dosage ƒ
·         Forms and protect them against damage or breakage. ƒ
·         It must not alter the identity of the product. ƒ
·         It must preserve the characteristics properties of the ƒ
·         Product to comply specifications. ƒ
·         It must protect product against undesirable or ƒ adulterating chemical, biological or physical entities.

Selection of packaging material
·    
  •     Moisture barrier requirements
  •     Light barrier requirements 
  •     Gas barrier requirements 
  •     Chemical properties

Choosing appropriate primary pack

Desiccants have been utilized to control the exposure of products to the ingress of moisture. Desiccants vary in their capacity and the rate that they adsorb/absorb ingressed moisture. Silica gel is very efficient at absorbing moisture at high relative humidity, but comparatively poor at lower Relative Humidity. Molecular sieve desiccants - the opposite scenario prevails.
As a consequence, more molecular sieve is required at higher relative humidity, and the greater the handling precautions that are required during packaging operations. Based on the calculated WVTR of known container components and the rate of moisture adsorbed by desiccants, the amount of desiccant that would be required to maintain a specified relative humidity over the product’s shelf-life can be determined and used. Also Read: Best guidelines for food packaging using LDPE bags.

TESTING AND STABILITY

  1. ·         Release of chemicals from components of packaging material
  2. ·         Release of visible and /or sub-visible particles 
  3. ·         Adsorption or absorption of pharmaceutical components by packaging material 
  4. ·         Chemical reaction between pharmaceutical productand packaging material 
  5. ·         Degradation of packaging component in contact with pharmaceutical products 
  6. ·         Influence of manufacturing process on the container


TESTING AND STABILITY
  • Vary according to the type of material used 
  • Visual inspection 
  • Identification test 
  •  Dimensional test 
  •  Physical tests 
  • Chemical tests 
  • Microbiological tests